The current standard of care for diabetic foot ulcers is debridement and moist wound therapy. This involves removing dead and damaged tissue, antibiotics (if infected), moist wound dressings, and reducing the pressure on the wound. In spite of moist wound therapy being the current standard of care, only 29% of wounds completely healed by 12 weeks.
Current advanced therapies such as hyperbaric oxygen and vacuum therapy are lengthy, inconvenient and have not shown significant improvements in outcome. They have relatively low patient compliance due to the length and difficulties of these therapies.
Even after all available therapies the recurrence rate is still close to 66%.